Not all patients with CLL have to have therapy. In spite of all the latest improvements, the iwCLL however recommends watchful observation for individuals with asymptomatic ailment.86 This suggestion is based on a minimum of two randomized trials comparing observation to both chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR). https://andersonf210oao4.wikikali.com/user