These outcomes, along with a past report showing that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like conduct in mice,2 support the notion of targeting ACKR3 as a unique strategy to modulate the opioid program, which could open new therapeutic avenues for opioid-associated disorders. By ticking this box and publishing https://johnt926wvu3.wikicarrier.com/user