Tramadol and its metabolite, O-desmethyltramadol (M1), are current in human milk. There isn't a information on the effects with the drug to the breastfed infant or the results in the drug on milk manufacturing. The M1 metabolite is more strong than tramadol in mu opioid receptor binding [see Scientific Pharmacology https://hansy208dko2.corpfinwiki.com/user